Bo Zhong Selected Research

nimesulide (Aulin)

5/2015	A rapid LC-MS/MS method for quantification of CSUOH0901, a novel antitumor agent, in rat plasma.
9/2012	Development and validation of a rapid LC-MS/MS method for the determination of JCC76, a novel antitumor agent for breast cancer, in rat plasma and its application to a pharmacokinetics study.
1/2012	From COX-2 inhibitor nimesulide to potent anti-cancer agent: synthesis, in vitro, in vivo and pharmacokinetic evaluation.
9/2011	Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76.
8/2011	In vitro and in vivo effects of a cyclooxygenase-2 inhibitor nimesulide analog JCC76 in aromatase inhibitors-insensitive breast cancer cells.

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Bo Zhong Research Topics

Disease

24	Neoplasms (Cancer) 01/2022 - 07/2011
22	Virus Diseases (Viral Diseases) 11/2020 - 07/2007
17	Infections 10/2020 - 01/2004
9	Pneumonia (Pneumonitis) 01/2022 - 03/2010
9	Bites and Stings (Sting) 01/2019 - 10/2014
8	Inflammation (Inflammations) 01/2020 - 06/2007
6	Schistosomiasis (Bilharziasis) 04/2017 - 12/2009
4	Asthma (Bronchial Asthma) 08/2021 - 03/2010
4	Brain Neoplasms (Brain Tumor) 09/2020 - 01/2019
4	Porcine Reproductive and Respiratory Syndrome (PRRS) 02/2018 - 08/2006
4	Breast Neoplasms (Breast Cancer) 06/2014 - 08/2011
3	Carcinogenesis 01/2022 - 01/2019
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2021 - 11/2020
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2020
2	Colitis 01/2022 - 01/2020
2	Colonic Neoplasms (Colon Cancer) 01/2022 - 01/2020
2	Adenocarcinoma of Lung 01/2021 - 07/2015
2	Glioma (Gliomas) 01/2021 - 01/2020
2	Lung Neoplasms (Lung Cancer) 01/2021 - 02/2016
2	DNA Virus Infections 11/2020 - 12/2016
2	Autoimmune Diseases (Autoimmune Disease) 10/2020 - 07/2011
2	Medulloblastoma 01/2020 - 01/2019
2	Neoplasm Metastasis (Metastasis) 01/2018 - 07/2015
2	Body Weight (Weight, Body) 09/2017 - 07/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 03/2014
2	Melanoma (Melanoma, Malignant) 12/2016 - 07/2010
2	Vesicular Stomatitis 01/2016 - 05/2009
2	Rheumatoid Arthritis 01/2014 - 08/2005
1	COVID-19 01/2022
1	Non-alcoholic Fatty Liver Disease 01/2022
1	Hyperalgesia 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Osteosarcoma (Osteogenic Sarcoma) 01/2021
1	RNA Virus Infections 01/2021
1	Esophageal Squamous Cell Carcinoma 01/2021

Drug/Important Bio-Agent (IBA)

24	Antiviral Agents (Antivirals)IBA 10/2020 - 10/2008
20	CytokinesIBA 01/2022 - 06/2007
16	Proteins (Proteins, Gene)FDA Link 08/2021 - 06/2010
16	Interferon Type IIBA 01/2019 - 10/2008
16	Transcription Factors (Transcription Factor)IBA 02/2018 - 06/2007
8	AntigensIBA 11/2019 - 03/2010
8	NF-kappa B (NF-kB)IBA 07/2010 - 06/2007
7	Pharmaceutical PreparationsIBA 01/2020 - 07/2011
7	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 10/2014
6	Ubiquitin-Specific ProteasesIBA 01/2020 - 07/2010
5	Deubiquitinating EnzymesIBA 01/2020 - 07/2010
5	Pattern Recognition ReceptorsIBA 02/2018 - 08/2006
5	nimesulide (Aulin)IBA 05/2015 - 08/2011
5	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 03/2015 - 07/2007
4	PolyubiquitinIBA 10/2020 - 01/2016
4	UbiquitinIBA 01/2019 - 03/2015
4	LigandsIBA 01/2018 - 06/2014
3	RNA (Ribonucleic Acid)IBA 11/2020 - 09/2015
3	Pathogen-Associated Molecular Pattern MoleculesIBA 02/2018 - 08/2006
3	Phosphotransferases (Kinase)IBA 02/2018 - 12/2010
3	Praziquantel (Biltricide)FDA Link 07/2016 - 07/2011
2	CateninsIBA 01/2022 - 01/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2021 - 06/2007
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021 - 12/2016
2	carboxyethylphosphoramide mustardIBA 01/2020 - 01/2019
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 01/2019
2	AntibodiesIBA 11/2019 - 04/2013
2	Nucleic AcidsIBA 02/2018 - 03/2015
2	InterferonsIBA 06/2016 - 05/2013
2	Indomethacin (Indometacin)FDA LinkGeneric 01/2016 - 10/2012
2	acetamideIBA 01/2016 - 03/2014
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2016 - 10/2012
2	TubulinIBA 01/2016 - 06/2014
2	TNF Receptor-Associated Factor 3IBA 09/2015 - 03/2010
2	TNF Receptor-Associated Factor 6 (TRAF6)IBA 09/2015 - 03/2010
2	benzo(1,3)dioxole-5-carboxylic acid (3- (2,5- dimethylbenzyloxy)- 4- (methanesulfonylmethylamino)phenyl)amideIBA 05/2015 - 01/2012
2	FertilizersIBA 01/2015 - 01/2004
2	Interleukin-17 (Interleukin 17)IBA 11/2012 - 07/2011
2	Interleukin-4 (Interleukin 4)IBA 04/2012 - 04/2011
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 04/2012 - 04/2010
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2012 - 08/2011
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2012 - 08/2011
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 06/2010 - 03/2009
1	1,4-dioxane (dioxane)IBA 01/2022
1	Dextran SulfateIBA 01/2022
1	Capsaicin (Zostrix)FDA Link 01/2022
1	TRPV Cation ChannelsIBA 01/2022
1	SolventsIBA 01/2022
1	Nonesterified Fatty Acids (NEFA)IBA 01/2022
1	LipidsIBA 01/2022
1	AntioxidantsIBA 10/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021
1	Glutathione (Reduced Glutathione)IBA 10/2021
1	HeterochromatinIBA 10/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2021
1	Viral RNAIBA 01/2021
1	Long Noncoding RNAIBA 01/2021
1	silmitasertibIBA 09/2020

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 01/2021 - 08/2008
3	Therapeutics 01/2020 - 01/2012
1	Craniotomy 01/2022
1	Length of Stay 01/2022
1	Immunotherapy 11/2020